YGL190C

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Systematic name YGL190C
Gene name CDC55
Aliases
Feature type ORF, Verified
Coordinates Chr VII:147389..145809
Primary SGDID S000003158


Description of YGL190C: Non-essential regulatory subunit B of protein phosphatase 2A (PP2A), which has multiple roles in mitosis and protein biosynthesis; involved in regulation of mitotic exit; found in the nucleus of most cells, also at bud neck and bud tip[1][2][3][4]




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References

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  1. Gentry MS and Hallberg RL (2002) Localization of Saccharomyces cerevisiae protein phosphatase 2A subunits throughout mitotic cell cycle. Mol Biol Cell 13(10):3477-92 SGD PMID 12388751
  2. Jiang Y and Broach JR (1999) Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast. EMBO J 18(10):2782-92 SGD PMID 10329624
  3. Queralt E, et al. (2006) Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast. Cell 125(4):719-32 SGD PMID 16713564
  4. Wang Y and Burke DJ (1997) Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae. Mol Cell Biol 17(2):620-6 SGD PMID 9001215

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