YGL181W
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Systematic name | YGL181W |
Gene name | GTS1 |
Aliases | FHT1, LSR1 |
Feature type | ORF, Verified |
Coordinates | Chr VII:157906..159096 |
Primary SGDID | S000003149 |
Description of YGL181W: Protein involved in Arf3p regulation and in transcription regulation; localizes to the nucleus and to endocytic patches; contains an N-terminal Zn-finger and ArfGAP homology domain, a C-terminal glutamine-rich region, and a UBA (ubiquitin associated) domain; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms, endocytosis; expression oscillates in a pattern similar to metabolic oscillations[1][2][3][4][5][6][7][8][9][10][11]
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References
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- ↑ Adams CA, et al. (2003) The Gts1 protein stabilizes the autonomous oscillator in yeast. Yeast 20(6):463-70 SGD PMID 12722180
- ↑ Bossier P, et al. (1997) Constitutive flocculation in Saccharomyces cerevisiae through overexpression of the GTS1 gene, coding for a 'Glo'-type Zn-finger-containing protein. Yeast 13(8):717-25 SGD PMID 9219336
- ↑ Mitsui K, et al. (1994) The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae. Mol Cell Biol 14(8):5569-78 SGD PMID 8035831
- ↑ Saito T, et al. (2002) Regulation of the Gts1p level by the ubiquitination system to maintain metabolic oscillations in the continuous culture of yeast. J Biol Chem 277(37):33624-31 SGD PMID 12070147
- ↑ Shen H, et al. (2006) The mechanism by which overexpression of Gts1p induces flocculation in a FLO8-inactive strain of the yeast Saccharomyces cerevisiae. FEMS Yeast Res 6(6):914-23 SGD PMID 16911513
- ↑ Smaczynska-de Rooij II, et al. (2008) Yeast Arf3p Modulates Plasma Membrane PtdIns(4,5)P2 Levels to Facilitate Endocytosis. Traffic 9(4):559-73 SGD PMID 18208507
- ↑ Tonozuka H, et al. (2001) Analysis of the upstream regulatory region of the GTS1 gene required for its oscillatory expression. J Biochem 130(5):589-95 SGD PMID 11686920
- ↑ Toret CP, et al. (2008) Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking. Traffic 9(5):848-59 SGD PMID 18298676
- ↑ Xu Z and Tsurugi K (2007) Role of Gts1p in regulation of energy-metabolism oscillation in continuous cultures of the yeast Saccharomyces cerevisiae. Yeast 24(3):161-70 SGD PMID 17351907
- ↑ Yaguchi S, et al. (1996) The pleiotropic effect of the GTS1 gene product on heat tolerance, sporulation and the life span of Saccharomyces cerevisiae. Biochem Biophys Res Commun 218(1):234-7 SGD PMID 8573138
- ↑ Yaguchi S, et al. (2007) Localization of Gts1p in cortical actin patches of yeast and its possible role in endocytosis. Eur J Cell Biol 86(5):275-85 SGD PMID 17449140
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