Difference between revisions of "YGL181W"

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'''Description of YGL181W:''' Protein that localizes to the nucleus and is involved in transcription regulation; also localizes to actin patches and plays a role in endocytosis; N-terminus contains an ARF-GAP domain and C-terminus contains a Gln-rich domain<ref name='S000049798'>Mitsui K, et al. (1994) The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae. Mol Cell Biol 14(8):5569-78 {{SGDpaper|S000049798}} PMID 8035831</ref><ref name='S000074013'>Yaguchi S and Tsurugi K (2003) Gts1p activates SNF1-dependent derepression of HSP104 and TPS1 in the stationary phase of yeast growth. J Biol Chem 278(32):29760-8 {{SGDpaper|S000074013}} PMID 12782635</ref><ref name='S000121362'>Xu Z and Tsurugi K (2007) Role of Gts1p in regulation of energy-metabolism oscillation in continuous cultures of the yeast Saccharomyces cerevisiae. Yeast 24(3):161-70 {{SGDpaper|S000121362}} PMID 17351907</ref><ref name='S000122481'>Yaguchi S, et al. (2007) Localization of Gts1p in cortical actin patches of yeast and its possible role in endocytosis. Eur J Cell Biol 86(5):275-85
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'''Description of YGL181W:''' Arf3p GTPase Activating Protein (GAP) that localizes to endocytic patches; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms; localizes to nucleus and induces flocculation when overexpressed<ref name='S000048465'>Yaguchi S, et al. (1996) The pleiotropic effect of the GTS1 gene product on heat tolerance, sporulation and the life span of Saccharomyces cerevisiae. Biochem Biophys Res Commun 218(1):234-7 {{SGDpaper|S000048465}} PMID 8573138</ref><ref name='S000048796'>Bossier P, et al. (1997) Constitutive flocculation in Saccharomyces cerevisiae through overexpression of the GTS1 gene, coding for a 'Glo'-type Zn-finger-containing protein. Yeast 13(8):717-25 {{SGDpaper|S000048796}} PMID 9219336</ref><ref name='S000049798'>Mitsui K, et al. (1994) The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae. Mol Cell Biol 14(8):5569-78 {{SGDpaper|S000049798}} PMID 8035831</ref><ref name='S000117953'>Shen H, et al. (2006) The mechanism by which overexpression of Gts1p induces flocculation in a FLO8-inactive strain of the yeast Saccharomyces cerevisiae. FEMS Yeast Res 6(6):914-23 {{SGDpaper|S000117953}} PMID 16911513</ref><ref name='S000072944'>Adams CA, et al. (2003) The Gts1 protein stabilizes the autonomous oscillator in yeast. Yeast 20(6):463-70 {{SGDpaper|S000072944}} PMID 12722180</ref><ref name='S000121362'>Xu Z and Tsurugi K (2007) Role of Gts1p in regulation of energy-metabolism oscillation in continuous cultures of the yeast Saccharomyces cerevisiae. Yeast 24(3):161-70 {{SGDpaper|S000121362}} PMID 17351907</ref><ref name='S000122481'>Yaguchi S, et al. (2007) Localization of Gts1p in cortical actin patches of yeast and its possible role in endocytosis. Eur J Cell Biol 86(5):275-85 {{SGDpaper|S000122481}} PMID 17449140</ref><ref name='S000125644'>Toret CP, et al. (2008) Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking. Traffic 9(5):848-59 {{SGDpaper|S000125644}} PMID 18298676</ref><ref name='S000125328'>Smaczynska-de Rooij II, et al. (2008) Yeast Arf3p Modulates Plasma Membrane PtdIns(4,5)P2 Levels to Facilitate Endocytosis. Traffic 9(4):559-73
  {{SGDpaper|S000122481}} PMID 17449140</ref>
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  {{SGDpaper|S000125328}} PMID 18208507</ref>
 
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Revision as of 14:05, 12 January 2010

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Systematic name YGL181W
Gene name GTS1
Aliases FHT1, LSR1
Feature type ORF, Verified
Coordinates Chr VII:157912..159102
Primary SGDID S000003149


Description of YGL181W: Arf3p GTPase Activating Protein (GAP) that localizes to endocytic patches; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms; localizes to nucleus and induces flocculation when overexpressed[1][2][3][4][5][6][7][8][9]




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References

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  1. Yaguchi S, et al. (1996) The pleiotropic effect of the GTS1 gene product on heat tolerance, sporulation and the life span of Saccharomyces cerevisiae. Biochem Biophys Res Commun 218(1):234-7 SGD PMID 8573138
  2. Bossier P, et al. (1997) Constitutive flocculation in Saccharomyces cerevisiae through overexpression of the GTS1 gene, coding for a 'Glo'-type Zn-finger-containing protein. Yeast 13(8):717-25 SGD PMID 9219336
  3. Mitsui K, et al. (1994) The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae. Mol Cell Biol 14(8):5569-78 SGD PMID 8035831
  4. Shen H, et al. (2006) The mechanism by which overexpression of Gts1p induces flocculation in a FLO8-inactive strain of the yeast Saccharomyces cerevisiae. FEMS Yeast Res 6(6):914-23 SGD PMID 16911513
  5. Adams CA, et al. (2003) The Gts1 protein stabilizes the autonomous oscillator in yeast. Yeast 20(6):463-70 SGD PMID 12722180
  6. Xu Z and Tsurugi K (2007) Role of Gts1p in regulation of energy-metabolism oscillation in continuous cultures of the yeast Saccharomyces cerevisiae. Yeast 24(3):161-70 SGD PMID 17351907
  7. Yaguchi S, et al. (2007) Localization of Gts1p in cortical actin patches of yeast and its possible role in endocytosis. Eur J Cell Biol 86(5):275-85 SGD PMID 17449140
  8. Toret CP, et al. (2008) Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking. Traffic 9(5):848-59 SGD PMID 18298676
  9. Smaczynska-de Rooij II, et al. (2008) Yeast Arf3p Modulates Plasma Membrane PtdIns(4,5)P2 Levels to Facilitate Endocytosis. Traffic 9(4):559-73 SGD PMID 18208507

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