Difference between revisions of "YGL180W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGL180W YGL180W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003148 YGL180W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:160071..162764
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|nowrap| Chr VII:160065..162758
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003148
 
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'''Description of {{PAGENAME}}:''' Protein serine/threonine kinase, required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway<ref name='S000072723'>Abeliovich H, et al. (2003) Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. Mol Biol Cell 14(2):477-90 {{SGDpaper|S000072723}} PMID 12589048</ref><ref name='S000046735'>Matsuura A, et al. (1997) Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 192(2):245-50 {{SGDpaper|S000046735}} PMID 9224897</ref><ref name='S000040285'>Straub M, et al. (1997) AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae. J Bacteriol 179(12):3875-83
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'''Description of YGL180W:''' Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p<ref name='S000072723'>Abeliovich H, et al. (2003) Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. Mol Biol Cell 14(2):477-90 {{SGDpaper|S000072723}} PMID 12589048</ref><ref name='S000124992'>Cheong H, et al. (2008) The Atg1 Kinase Complex Is Involved in the Regulation of Protein Recruitment to Initiate Sequestering Vesicle Formation for Nonspecific Autophagy in Saccharomyces cerevisiae. Mol Biol Cell 19(2):668-81 {{SGDpaper|S000124992}} PMID 18077553</ref><ref name='S000080939'>Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 {{SGDpaper|S000080939}} PMID 15743910</ref><ref name='S000046735'>Matsuura A, et al. (1997) Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 192(2):245-50 {{SGDpaper|S000046735}} PMID 9224897</ref><ref name='S000040285'>Straub M, et al. (1997) AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae. J Bacteriol 179(12):3875-83
 
  {{SGDpaper|S000040285}} PMID 9190802</ref>
 
  {{SGDpaper|S000040285}} PMID 9190802</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGL180W
Gene name ATG1
Aliases APG1, AUT3, CVT10
Feature type ORF, Verified
Coordinates Chr VII:160065..162758
Primary SGDID S000003148


Description of YGL180W: Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p[1][2][3][4][5]




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References

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  1. Abeliovich H, et al. (2003) Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. Mol Biol Cell 14(2):477-90 SGD PMID 12589048
  2. Cheong H, et al. (2008) The Atg1 Kinase Complex Is Involved in the Regulation of Protein Recruitment to Initiate Sequestering Vesicle Formation for Nonspecific Autophagy in Saccharomyces cerevisiae. Mol Biol Cell 19(2):668-81 SGD PMID 18077553
  3. Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 SGD PMID 15743910
  4. Matsuura A, et al. (1997) Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 192(2):245-50 SGD PMID 9224897
  5. Straub M, et al. (1997) AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae. J Bacteriol 179(12):3875-83 SGD PMID 9190802

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