YGL178W
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| Systematic name | YGL178W |
| Gene name | MPT5 |
| Aliases | HTR1, PUF5, UTH4 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:167358..170577 |
| Primary SGDID | S000003146 |
Description of YGL178W: Member of the Puf family of RNA-binding proteins; binds to mRNAs encoding chromatin modifiers and spindle pole body components; involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest[1][2][3][4][5]
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References
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- ↑ Kennedy BK, et al. (1997) Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell 89(3):381-91 SGD PMID 9150138
- ↑ Chen T and Kurjan J (1997) Saccharomyces cerevisiae Mpt5p interacts with Sst2p and plays roles in pheromone sensitivity and recovery from pheromone arrest. Mol Cell Biol 17(6):3429-39 SGD PMID 9154842
- ↑ Tadauchi T, et al. (2001) Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBF. EMBO J 20(3):552-61 SGD PMID 11157761
- ↑ Gerber AP, et al. (2004) Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol 2(3):E79 SGD PMID 15024427
- ↑ Kaeberlein M and Guarente L (2002) Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity. Genetics 160(1):83-95 SGD PMID 11805047
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