Difference between revisions of "YGL173C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003141 YGL173C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KEM1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KEM1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VII:180119..175533 | |nowrap| Chr VII:180119..175533 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003141 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YGL173C:''' Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000073211'>Sheth U and Parker R (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300(5620):805-8 {{SGDpaper|S000073211}} PMID 12730603</ref><ref name='S000071615'>Kim J and Kim J (2002) KEM1 is involved in filamentous growth of Saccharomyces cerevisiae. FEMS Microbiol Lett 216(1):33-8 {{SGDpaper|S000071615}} PMID 12423748</ref><ref name='S000059142'>Geerlings TH, et al. (2000) The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5'-->3' exonucleases. RNA 6(12):1698-703 {{SGDpaper|S000059142}} PMID 11142370</ref><ref name='S000052508'>Solinger JA, et al. (1999) Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis. Mol Cell Biol 19(9):5930-42 |
{{SGDpaper|S000052508}} PMID 10454540</ref> | {{SGDpaper|S000052508}} PMID 10454540</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL173C |
| Gene name | KEM1 |
| Aliases | DST2, RAR5, SEP1, SKI1, XRN1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:180119..175533 |
| Primary SGDID | S000003141 |
Description of YGL173C: Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance[1][2][3][4][5]
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References
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- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Sheth U and Parker R (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300(5620):805-8 SGD PMID 12730603
- ↑ Kim J and Kim J (2002) KEM1 is involved in filamentous growth of Saccharomyces cerevisiae. FEMS Microbiol Lett 216(1):33-8 SGD PMID 12423748
- ↑ Geerlings TH, et al. (2000) The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5'-->3' exonucleases. RNA 6(12):1698-703 SGD PMID 11142370
- ↑ Solinger JA, et al. (1999) Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis. Mol Cell Biol 19(9):5930-42 SGD PMID 10454540
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