Difference between revisions of "YGL172W"
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| − | '''Description of YGL172W:''' | + | '''Description of YGL172W:''' FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nic96p and two other FG-nucleoproteins (Nsp1p and Nup57p)<ref name='S000061454'>Allen NP, et al. (2001) Proteomic analysis of nucleoporin interacting proteins. J Biol Chem 276(31):29268-74 {{SGDpaper|S000061454}} PMID 11387327</ref><ref name='S000057498'>Doye V, et al. (1994) A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution. EMBO J 13(24):6062-75 {{SGDpaper|S000057498}} PMID 7813444</ref><ref name='S000145464'>Frey S and Gorlich D (2009) FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J 28(17):2554-67 {{SGDpaper|S000145464}} PMID 19680227</ref><ref name='S000040785'>Grandi P, et al. (1993) Purification of NSP1 reveals complex formation with 'GLFG' nucleoporins and a novel nuclear pore protein NIC96. EMBO J 12(8):3061-71 {{SGDpaper|S000040785}} PMID 7688296</ref><ref name='S000044179'>Hurt E, et al. (1999) A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants. J Cell Biol 144(3):389-401 {{SGDpaper|S000044179}} PMID 9971735</ref><ref name='S000086510'>Lutzmann M, et al. (2005) Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem 280(18):18442-51 {{SGDpaper|S000086510}} PMID 15741174</ref><ref name='S000122438'>Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 {{SGDpaper|S000122438}} PMID 17418788</ref><ref name='S000052060'>Sharma K, et al. (1996) Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol Cell Biol 16(1):294-301 {{SGDpaper|S000052060}} PMID 8524308</ref><ref name='S000059349'>Stage-Zimmermann T, et al. (2000) Factors affecting nuclear export of the 60S ribosomal subunit in vivo. Mol Biol Cell 11(11):3777-89 |
| − | {{SGDpaper| | + | {{SGDpaper|S000059349}} PMID 11071906</ref> |
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Latest revision as of 14:05, 19 June 2012
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| Systematic name | YGL172W |
| Gene name | NUP49 |
| Aliases | NSP49 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:180700..182118 |
| Primary SGDID | S000003140 |
Description of YGL172W: FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nic96p and two other FG-nucleoproteins (Nsp1p and Nup57p)[1][2][3][4][5][6][7][8][9]
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References
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- ↑ Allen NP, et al. (2001) Proteomic analysis of nucleoporin interacting proteins. J Biol Chem 276(31):29268-74 SGD PMID 11387327
- ↑ Doye V, et al. (1994) A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution. EMBO J 13(24):6062-75 SGD PMID 7813444
- ↑ Frey S and Gorlich D (2009) FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J 28(17):2554-67 SGD PMID 19680227
- ↑ Grandi P, et al. (1993) Purification of NSP1 reveals complex formation with 'GLFG' nucleoporins and a novel nuclear pore protein NIC96. EMBO J 12(8):3061-71 SGD PMID 7688296
- ↑ Hurt E, et al. (1999) A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants. J Cell Biol 144(3):389-401 SGD PMID 9971735
- ↑ Lutzmann M, et al. (2005) Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem 280(18):18442-51 SGD PMID 15741174
- ↑ Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 SGD PMID 17418788
- ↑ Sharma K, et al. (1996) Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol Cell Biol 16(1):294-301 SGD PMID 8524308
- ↑ Stage-Zimmermann T, et al. (2000) Factors affecting nuclear export of the 60S ribosomal subunit in vivo. Mol Biol Cell 11(11):3777-89 SGD PMID 11071906
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