YGL156W

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Systematic name YGL156W
Gene name AMS1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:210421..213672
Primary SGDID S000003124


Description of YGL156W: Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway[1][2][3]




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References

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  1. Yoshihisa T and Anraku Y (1990) A novel pathway of import of alpha-mannosidase, a marker enzyme of vacuolar membrane, in Saccharomyces cerevisiae. J Biol Chem 265(36):22418-25 SGD PMID 2266133
  2. Hutchins MU and Klionsky DJ (2001) Vacuolar localization of oligomeric alpha-mannosidase requires the cytoplasm to vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae. J Biol Chem 276(23):20491-8 SGD PMID 11264288
  3. Chantret I, et al. (2003) Free-oligosaccharide control in the yeast Saccharomyces cerevisiae: roles for peptide:N-glycanase (Png1p) and vacuolar mannosidase (Ams1p). Biochem J 373(Pt 3):901-8 SGD PMID 12723970

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