YGL143C
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| Systematic name | YGL143C | |
| Gene name | MRF1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr VII:235963..234722 | |
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Description of YGL143C: Mitochondrial polypeptide chain release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability[1][2]
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References
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- ↑ Towpik J, et al. (2004) Mutations in the yeast mrf1 gene encoding mitochondrial release factor inhibit translation on mitochondrial ribosomes. J Biol Chem 279(14):14096-103 SGD PMID 14734569
- ↑ Pel HJ, et al. (1992) The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects. Nucleic Acids Res 20(23):6339-46 SGD PMID 1475194
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