YGL119W

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Systematic name YGL119W
Gene name ABC1
Aliases COQ8
Feature type ORF, Verified
Coordinates Chr VII:284448..285953
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Description of YGL119W: Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis[1][2][3][4]



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References

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  1. Johnson A, et al. (2005) COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem 280(36):31397-404 SGD PMID 16027161
  2. Do TQ, et al. (2001) A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants. J Biol Chem 276(21):18161-8 SGD PMID 11279158
  3. Bousquet I, et al. (1991) ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex. EMBO J 10(8):2023-31 SGD PMID 1648478
  4. Poon WW, et al. (2000) Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. J Bacteriol 182(18):5139-46 SGD PMID 10960098

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