YGL092W

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Systematic name YGL092W
Gene name NUP145
Aliases RAT10
Feature type ORF, Verified
Coordinates Chr VII:337909..341862


Description of YGL092W: Essential nucleoporin, catalyzes its own cleavage in vivo to generate a C-terminal fragment that assembles into the Nup84p subcomplex of the nuclear pore complex, and an N-terminal fragment of unknown function that is homologous to Nup100p[1][2]




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References

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  1. Teixeira MT, et al. (1997) Two functionally distinct domains generated by in vivo cleavage of Nup145p: a novel biogenesis pathway for nucleoporins. EMBO J 16(16):5086-97 SGD PMID 9305650
  2. Teixeira MT, et al. (1999) Self-catalyzed cleavage of the yeast nucleoporin Nup145p precursor. J Biol Chem 274(45):32439-44 SGD PMID 10542288

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