YGL065C

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Systematic name YGL065C
Gene name ALG2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:381274..379763
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Description of YGL065C: Presumed early mannosyltransferase involved in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol[1][2][3]



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References

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  1. Burda P and Aebi M (1999) The dolichol pathway of N-linked glycosylation. Biochim Biophys Acta 1426(2):239-57 SGD PMID 9878760
  2. Jackson BJ, et al. (1993) Biosynthesis of asparagine-linked oligosaccharides in Saccharomyces cerevisiae: the alg2 mutation. Glycobiology 3(4):357-64 SGD PMID 8400550
  3. Huffaker TC and Robbins PW (1983) Yeast mutants deficient in protein glycosylation. Proc Natl Acad Sci U S A 80(24):7466-70 SGD PMID 6369318

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