Difference between revisions of "YGL065C"
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| − | '''Description of YGL065C:''' | + | '''Description of YGL065C:''' Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol<ref name='S000117548'>O'Reilly MK, et al. (2006) In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis. Biochemistry 45(31):9593-603 {{SGDpaper|S000117548}} PMID 16878994</ref><ref name='S000058396'>Burda P and Aebi M (1999) The dolichol pathway of N-linked glycosylation. Biochim Biophys Acta 1426(2):239-57 {{SGDpaper|S000058396}} PMID 9878760</ref><ref name='S000051786'>Jackson BJ, et al. (1993) Biosynthesis of asparagine-linked oligosaccharides in Saccharomyces cerevisiae: the alg2 mutation. Glycobiology 3(4):357-64 {{SGDpaper|S000051786}} PMID 8400550</ref><ref name='S000046125'>Huffaker TC and Robbins PW (1983) Yeast mutants deficient in protein glycosylation. Proc Natl Acad Sci U S A 80(24):7466-70 |
{{SGDpaper|S000046125}} PMID 6369318</ref> | {{SGDpaper|S000046125}} PMID 6369318</ref> | ||
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Revision as of 14:05, 17 April 2007
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| Systematic name | YGL065C |
| Gene name | ALG2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:381274..379763 |
| Primary SGDID | S000003033 |
Description of YGL065C: Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol[1][2][3][4]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [5] [6]
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References
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- ↑ O'Reilly MK, et al. (2006) In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis. Biochemistry 45(31):9593-603 SGD PMID 16878994
- ↑ Burda P and Aebi M (1999) The dolichol pathway of N-linked glycosylation. Biochim Biophys Acta 1426(2):239-57 SGD PMID 9878760
- ↑ Jackson BJ, et al. (1993) Biosynthesis of asparagine-linked oligosaccharides in Saccharomyces cerevisiae: the alg2 mutation. Glycobiology 3(4):357-64 SGD PMID 8400550
- ↑ Huffaker TC and Robbins PW (1983) Yeast mutants deficient in protein glycosylation. Proc Natl Acad Sci U S A 80(24):7466-70 SGD PMID 6369318
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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