Difference between revisions of "YGL058W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003026 YGL058W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003026 YGL058W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD6 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD6 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:393992..394510
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|nowrap| Chr VII:393986..394504
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003026
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003026
 
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'''Description of YGL058W:''' Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)<ref name='S000049161'>Jentsch S, et al. (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329(6135):131-4 {{SGDpaper|S000049161}} PMID 3306404</ref><ref name='S000051450'>Bailly V, et al. (1997) Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J Biol Chem 272(37):23360-5 {{SGDpaper|S000051450}} PMID 9287349</ref><ref name='S000061431'>Broomfield S, et al. (2001) DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae. Mutat Res 486(3):167-84
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'''Description of YGL058W:''' Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (as a heterodimer with Rad18p), DSBR and checkpoint control (as a heterodimer with Bre1p), ubiquitin-mediated N-end rule protein degradation (as a heterodimer with Ubr1p<ref name='S000129404'>Game JC and Chernikova SB (2009) The role of RAD6 in recombinational repair, checkpoints and meiosis via histone modification. DNA Repair (Amst) 8(4):470-82 {{SGDpaper|S000129404}} PMID 19230796</ref><ref name='S000049161'>Jentsch S, et al. (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329(6135):131-4 {{SGDpaper|S000049161}} PMID 3306404</ref><ref name='S000131245'>Ulrich HD (2009) Regulating post-translational modifications of the eukaryotic replication clamp PCNA. DNA Repair (Amst) 8(4):461-9 {{SGDpaper|S000131245}} PMID 19217833</ref><ref name='S000061761'>Varshavsky A (1996) The N-end rule: functions, mysteries, uses. Proc Natl Acad Sci U S A 93(22):12142-9
  {{SGDpaper|S000061431}} PMID 11459630</ref>
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  {{SGDpaper|S000061761}} PMID 8901547</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGL058W
Gene name RAD6
Aliases PSO8, UBC2
Feature type ORF, Verified
Coordinates Chr VII:393986..394504
Primary SGDID S000003026


Description of YGL058W: Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (as a heterodimer with Rad18p), DSBR and checkpoint control (as a heterodimer with Bre1p), ubiquitin-mediated N-end rule protein degradation (as a heterodimer with Ubr1p[1][2][3][4]




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References

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  1. Game JC and Chernikova SB (2009) The role of RAD6 in recombinational repair, checkpoints and meiosis via histone modification. DNA Repair (Amst) 8(4):470-82 SGD PMID 19230796
  2. Jentsch S, et al. (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329(6135):131-4 SGD PMID 3306404
  3. Ulrich HD (2009) Regulating post-translational modifications of the eukaryotic replication clamp PCNA. DNA Repair (Amst) 8(4):461-9 SGD PMID 19217833
  4. Varshavsky A (1996) The N-end rule: functions, mysteries, uses. Proc Natl Acad Sci U S A 93(22):12142-9 SGD PMID 8901547

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