Difference between revisions of "YGL044C"
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| − | '''Description of YGL044C:''' Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay<ref name='S000060315'>Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 {{SGDpaper|S000060315}} PMID 11344258</ref><ref name='S000068788'>Gross S and Moore CL (2001) Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation. Mol Cell Biol 21(23):8045-55 {{SGDpaper|S000068788}} PMID 11689695</ref><ref name='S000146226'>Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 | + | '''Description of YGL044C:''' Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping<ref name='S000060315'>Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 {{SGDpaper|S000060315}} PMID 11344258</ref><ref name='S000068788'>Gross S and Moore CL (2001) Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation. Mol Cell Biol 21(23):8045-55 {{SGDpaper|S000068788}} PMID 11689695</ref><ref name='S000146442'>Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () {{SGDpaper|S000146442}} PMID 21835917</ref><ref name='S000146226'>Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 |
{{SGDpaper|S000146226}} PMID 21478823</ref> | {{SGDpaper|S000146226}} PMID 21478823</ref> | ||
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Revision as of 14:05, 30 August 2011
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| Systematic name | YGL044C |
| Gene name | RNA15 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:417036..416146 |
| Primary SGDID | S000003012 |
Description of YGL044C: Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping[1][2][3][4]
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References
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- ↑ Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 SGD PMID 11344258
- ↑ Gross S and Moore CL (2001) Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation. Mol Cell Biol 21(23):8045-55 SGD PMID 11689695
- ↑ Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () SGD PMID 21835917
- ↑ Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 SGD PMID 21478823
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