Difference between revisions of "YGL035C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGL035C YGL035C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003003 YGL035C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MIG1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MIG1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:433067..431553
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|nowrap| Chr VII:433062..431548
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003003
 
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'''Description of {{PAGENAME}}:''' Transcription factor involved in glucose repression; C2H2 zinc finger protein similar to mammalian Egr and Wilms tumor proteins<ref name='S000053925'>Nehlin JO and Ronne H (1990) Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins. EMBO J 9(9):2891-8 {{SGDpaper|S000053925}} PMID 2167835</ref><ref name='S000051138'>Griggs DW and Johnston M (1991) Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression. Proc Natl Acad Sci U S A 88(19):8597-601 {{SGDpaper|S000051138}} PMID 1924319</ref><ref name='S000049019'>Nehlin JO, et al. (1991) Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response. EMBO J 10(11):3373-7
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'''Description of YGL035C:''' Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase<ref name='S000046271'>Lundin M, et al. (1994) Importance of a flanking AT-rich region in target site recognition by the GC box-binding zinc finger protein MIG1. Mol Cell Biol 14(3):1979-85 {{SGDpaper|S000046271}} PMID 8114729</ref><ref name='S000053925'>Nehlin JO and Ronne H (1990) Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins. EMBO J 9(9):2891-8 {{SGDpaper|S000053925}} PMID 2167835</ref><ref name='S000114661'>Santangelo GM (2006) Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 70(1):253-82 {{SGDpaper|S000114661}} PMID 16524925</ref><ref name='S000073587'>Schuller HJ (2003) Transcriptional control of nonfermentative metabolism in the yeast Saccharomyces cerevisiae. Curr Genet 43(3):139-60
  {{SGDpaper|S000049019}} PMID 1915298</ref>
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  {{SGDpaper|S000073587}} PMID 12715202</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Regulatory ====
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SNF3 expression is repressed by high levels of glucose, via the Snf1-Mig1 glucose repression pathway. <ref name='S000054594'>Ozcan S, et al. (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17(9):2566-73 {{SGDpaper|S000054594}} PMID 9564039</ref> <ref name = 'CAset2827-2003-03-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2827 Mark Johnston] on 2003-03-11</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGL035C
Gene name MIG1
Aliases CAT4, SSN1, TDS22
Feature type ORF, Verified
Coordinates Chr VII:433062..431548
Primary SGDID S000003003


Description of YGL035C: Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase[1][2][3][4]




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Community Commentary

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Interactions

Regulatory

SNF3 expression is repressed by high levels of glucose, via the Snf1-Mig1 glucose repression pathway. [5] [6]





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References

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  1. Lundin M, et al. (1994) Importance of a flanking AT-rich region in target site recognition by the GC box-binding zinc finger protein MIG1. Mol Cell Biol 14(3):1979-85 SGD PMID 8114729
  2. Nehlin JO and Ronne H (1990) Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins. EMBO J 9(9):2891-8 SGD PMID 2167835
  3. Santangelo GM (2006) Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 70(1):253-82 SGD PMID 16524925
  4. Schuller HJ (2003) Transcriptional control of nonfermentative metabolism in the yeast Saccharomyces cerevisiae. Curr Genet 43(3):139-60 SGD PMID 12715202
  5. Ozcan S, et al. (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17(9):2566-73 SGD PMID 9564039
  6. submitted by Mark Johnston on 2003-03-11

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