YGL025C
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| Systematic name | YGL025C |
| Gene name | PGD1 |
| Aliases | HRS1, MED3 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:449962..448769 |
Description of YGL025C: Subunit of the Mediator global transcriptional cofactor complex, which is part of the RNA polymerase II holoenzyme and plays an essential role in basal and activated transcription; direct target of the Cyc8p-Tup1p transcriptional corepressor[1][2][3][4]
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References
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- ↑ Myers LC, et al. (1999) Mediator protein mutations that selectively abolish activated transcription. Proc Natl Acad Sci U S A 96(1):67-72 SGD PMID 9874773
- ↑ Reeves WM and Hahn S (2003) Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation. Mol Cell Biol 23(1):349-58 SGD PMID 12482986
- ↑ Lee M, et al. (2000) Genetic analysis of the role of Pol II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast. Genetics 155(4):1535-42 SGD PMID 10924455
- ↑ Papamichos-Chronakis M, et al. (2000) Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme. J Biol Chem 275(12):8397-403 SGD PMID 10722672
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