Difference between revisions of "YGL025C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002993 YGL025C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002993 YGL025C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PGD1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PGD1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:449962..448769
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|nowrap| Chr VII:449957..448764
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002993
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002993

Latest revision as of 07:45, 23 January 2012

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Systematic name YGL025C
Gene name PGD1
Aliases HRS1, MED3
Feature type ORF, Verified
Coordinates Chr VII:449957..448764
Primary SGDID S000002993


Description of YGL025C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor[1][2][3][4][5]




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References

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  1. Guglielmi B, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91 SGD PMID 15477388
  2. Lee M, et al. (2000) Genetic analysis of the role of Pol II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast. Genetics 155(4):1535-42 SGD PMID 10924455
  3. Myers LC, et al. (1999) Mediator protein mutations that selectively abolish activated transcription. Proc Natl Acad Sci U S A 96(1):67-72 SGD PMID 9874773
  4. Papamichos-Chronakis M, et al. (2000) Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme. J Biol Chem 275(12):8397-403 SGD PMID 10722672
  5. Reeves WM and Hahn S (2003) Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation. Mol Cell Biol 23(1):349-58 SGD PMID 12482986

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