Difference between revisions of "YGL021W"

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'''Description of YGL021W:''' Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins<ref name='S000060073'>Chen WN, et al. (1991) The YGL021 gene encodes a putative membrane protein with a putative leucine zipper motif. Yeast 7(3):301-3 {{SGDpaper|S000060073}} PMID 1882554</ref><ref name='S000073149'>Higgins JM (2003) Structure, function and evolution of haspin and haspin-related proteins, a distinctive group of eukaryotic protein kinases. Cell Mol Life Sci 60(3):446-62 {{SGDpaper|S000073149}} PMID 12737306</ref><ref name='S000117268'>Nespoli A, et al. (2006) Alk1 and Alk2 are two new cell cycle-regulated haspin-like proteins in budding yeast. Cell Cycle 5(13):1464-71
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'''Description of YGL021W:''' Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins<ref name='S000117268'>Nespoli A, et al. (2006) Alk1 and Alk2 are two new cell cycle-regulated haspin-like proteins in budding yeast. Cell Cycle 5(13):1464-71 {{SGDpaper|S000117268}} PMID 16855400</ref><ref name='S000073149'>Higgins JM (2003) Structure, function and evolution of haspin and haspin-related proteins, a distinctive group of eukaryotic protein kinases. Cell Mol Life Sci 60(3):446-62 {{SGDpaper|S000073149}} PMID 12737306</ref><ref name='S000060073'>Chen WN, et al. (1991) The YGL021 gene encodes a putative membrane protein with a putative leucine zipper motif. Yeast 7(3):301-3
  {{SGDpaper|S000117268}} PMID 16855400</ref>
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  {{SGDpaper|S000060073}} PMID 1882554</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YGL021W
Gene name ALK1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:454790..457072
Primary SGDID S000002989


Description of YGL021W: Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins[1][2][3]




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References

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  1. Nespoli A, et al. (2006) Alk1 and Alk2 are two new cell cycle-regulated haspin-like proteins in budding yeast. Cell Cycle 5(13):1464-71 SGD PMID 16855400
  2. Higgins JM (2003) Structure, function and evolution of haspin and haspin-related proteins, a distinctive group of eukaryotic protein kinases. Cell Mol Life Sci 60(3):446-62 SGD PMID 12737306
  3. Chen WN, et al. (1991) The YGL021 gene encodes a putative membrane protein with a putative leucine zipper motif. Yeast 7(3):301-3 SGD PMID 1882554

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