YGL011C

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Systematic name YGL011C
Gene name SCL1
Aliases PRC2
Feature type ORF, Verified
Coordinates Chr VII:475252..474494
Primary SGDID S000002979


Description of YGL011C: Alpha 1 subunit of the 20S proteasome involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria[1][2][3][4]




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References

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  1. Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
  2. Emori Y, et al. (1991) Molecular cloning and functional analysis of three subunits of yeast proteasome. Mol Cell Biol 11(1):344-53 SGD PMID 1898763
  3. Lee DH, et al. (1991) Molecular cloning of the yeast proteasome PRS2 gene identical to the suppressor gene scl1+. Biochem Int 23(4):689-96 SGD PMID 1872882
  4. Groll M, et al. (1997) Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386(6624):463-71 SGD PMID 9087403

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