Difference between revisions of "YGL006W"

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'''Description of YGL006W:''' Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a<ref name='S000042399'>Marchi V, et al. (1999) Induction of vacuolar Ca2+-ATPase and H+/Ca2+ exchange activity in yeast mutants lacking Pmr1, the Golgi Ca2+-ATPase. FEBS Lett 454(3):181-6 {{SGDpaper|S000042399}} PMID 10431803</ref><ref name='S000042898'>Cunningham KW and Fink GR (1994) Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases. J Cell Biol 124(3):351-63
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'''Description of YGL006W:''' Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a<ref name='S000042898'>Cunningham KW and Fink GR (1994) Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases. J Cell Biol 124(3):351-63 {{SGDpaper|S000042898}} PMID 7507493</ref><ref name='S000042399'>Marchi V, et al. (1999) Induction of vacuolar Ca2+-ATPase and H+/Ca2+ exchange activity in yeast mutants lacking Pmr1, the Golgi Ca2+-ATPase. FEBS Lett 454(3):181-6
{{SGDpaper|S000042898}} PMID 7507493</ref>
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{{SGDpaper|S000042399}} PMID 10431803</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YGL006W
Gene name PMC1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:485925..489446
Primary SGDID S000002974


Description of YGL006W: Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a[1][2]




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References

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  1. Cunningham KW and Fink GR (1994) Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases. J Cell Biol 124(3):351-63 SGD PMID 7507493
  2. Marchi V, et al. (1999) Induction of vacuolar Ca2+-ATPase and H+/Ca2+ exchange activity in yeast mutants lacking Pmr1, the Golgi Ca2+-ATPase. FEBS Lett 454(3):181-6 SGD PMID 10431803

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