YFR044C

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Systematic name YFR044C
Gene name DUG1
Aliases
Feature type ORF, Verified
Coordinates Chr VI:241424..239979


Description of YFR044C: Probable di- and tri-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)[1]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [2] [3]




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References

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  1. Ganguli D, et al. (2006) The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae. Genetics () SGD PMID 17179087
  2. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  3. submitted by Steffen Ohlmeier on 2004-04-08

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