Difference between revisions of "YFR034C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YFR034C YFR034C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001930 YFR034C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO4 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''phoD''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VI:225946..225008
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|nowrap| Chr VI:225958..225020
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001930
 
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'''Description of {{PAGENAME}}:''' Basic helix-loop-helix (bHLH) transcription factor; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability<ref name='S000049188'>Ogawa N and Oshima Y (1990) Functional domains of a positive regulatory protein, PHO4, for transcriptional control of the phosphatase regulon in Saccharomyces cerevisiae. Mol Cell Biol 10(5):2224-36 {{SGDpaper|S000049188}} PMID 2183025</ref><ref name='S000047164'>Berben G, et al. (1990) The yeast regulatory gene PHO4 encodes a helix-loop-helix motif. Yeast 6(5):451-4 {{SGDpaper|S000047164}} PMID 2220078</ref><ref name='S000046458'>Komeili A and O'Shea EK (1999) Roles of phosphorylation sites in regulating activity of the transcription factor Pho4. Science 284(5416):977-80
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'''Description of YFR034C:''' Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p,; function is regulated by phosphorylation at multiple sites and by phosphate availability<ref name='S000047164'>Berben G, et al. (1990) The yeast regulatory gene PHO4 encodes a helix-loop-helix motif. Yeast 6(5):451-4 {{SGDpaper|S000047164}} PMID 2220078</ref><ref name='S000046458'>Komeili A and O'Shea EK (1999) Roles of phosphorylation sites in regulating activity of the transcription factor Pho4. Science 284(5416):977-80 {{SGDpaper|S000046458}} PMID 10320381</ref><ref name='S000049188'>Ogawa N and Oshima Y (1990) Functional domains of a positive regulatory protein, PHO4, for transcriptional control of the phosphatase regulon in Saccharomyces cerevisiae. Mol Cell Biol 10(5):2224-36 {{SGDpaper|S000049188}} PMID 2183025</ref><ref name='S000145916'>Zhou X and O'Shea EK (2011) Integrated Approaches Reveal Determinants of Genome-wide Binding and Function of the Transcription Factor Pho4. Mol Cell 42(6):826-36
  {{SGDpaper|S000046458}} PMID 10320381</ref>
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  {{SGDpaper|S000145916}} PMID 21700227</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YFR034C
Gene name PHO4
Aliases phoD
Feature type ORF, Verified
Coordinates Chr VI:225958..225020
Primary SGDID S000001930


Description of YFR034C: Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p,; function is regulated by phosphorylation at multiple sites and by phosphate availability[1][2][3][4]




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Community Commentary

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References

See Help:References on how to add references

  1. Berben G, et al. (1990) The yeast regulatory gene PHO4 encodes a helix-loop-helix motif. Yeast 6(5):451-4 SGD PMID 2220078
  2. Komeili A and O'Shea EK (1999) Roles of phosphorylation sites in regulating activity of the transcription factor Pho4. Science 284(5416):977-80 SGD PMID 10320381
  3. Ogawa N and Oshima Y (1990) Functional domains of a positive regulatory protein, PHO4, for transcriptional control of the phosphatase regulon in Saccharomyces cerevisiae. Mol Cell Biol 10(5):2224-36 SGD PMID 2183025
  4. Zhou X and O'Shea EK (2011) Integrated Approaches Reveal Determinants of Genome-wide Binding and Function of the Transcription Factor Pho4. Mol Cell 42(6):826-36 SGD PMID 21700227

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