Difference between revisions of "YFR027W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001923 YFR027W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ECO1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ECO1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VI:207440..208285 | |nowrap| Chr VI:207440..208285 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001923 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YFR027W:''' Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication, but not for its maintenance during G2 and M phases; also required for postreplicative double-strand break repair; interacts with Chl1p<ref name='S000076406'>Skibbens RV (2004) Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion. Genetics 166(1):33-42 {{SGDpaper|S000076406}} PMID 15020404</ref><ref name='S000069235'>Ivanov D, et al. (2002) Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion. Curr Biol 12(4):323-8 {{SGDpaper|S000069235}} PMID 11864574</ref><ref name='S000060869'>Sjogren C and Nasmyth K (2001) Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Curr Biol 11(12):991-5 {{SGDpaper|S000060869}} PMID 11448778</ref><ref name='S000049776'>Toth A, et al. (1999) Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes Dev 13(3):320-33 {{SGDpaper|S000049776}} PMID 9990856</ref><ref name='S000049775'>Skibbens RV, et al. (1999) Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery. Genes Dev 13(3):307-19 |
{{SGDpaper|S000049775}} PMID 9990855</ref> | {{SGDpaper|S000049775}} PMID 9990855</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YFR027W |
| Gene name | ECO1 |
| Aliases | CTF7 |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:207440..208285 |
| Primary SGDID | S000001923 |
Description of YFR027W: Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication, but not for its maintenance during G2 and M phases; also required for postreplicative double-strand break repair; interacts with Chl1p[1][2][3][4][5]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [6] [7]
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References
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- ↑ Skibbens RV (2004) Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion. Genetics 166(1):33-42 SGD PMID 15020404
- ↑ Ivanov D, et al. (2002) Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion. Curr Biol 12(4):323-8 SGD PMID 11864574
- ↑ Sjogren C and Nasmyth K (2001) Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Curr Biol 11(12):991-5 SGD PMID 11448778
- ↑ Toth A, et al. (1999) Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes Dev 13(3):320-33 SGD PMID 9990856
- ↑ Skibbens RV, et al. (1999) Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery. Genes Dev 13(3):307-19 SGD PMID 9990855
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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