YFR021W

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Systematic name YFR021W
Gene name ATG18
Aliases AUT10, CVT18, NMR1, SVP1
Feature type ORF, Verified
Coordinates Chr VI:194800..196302
Primary SGDID S000001917


Description of YFR021W: Phosphatidylinositol 3,5-bisphosphate-binding protein of the vacuolar membrane, predicted to fold as a seven-bladed beta-propeller; required for recycling of Atg9p through the pre-autophagosomal structure[1][2][3]




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References

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  1. Dove SK, et al. (2004) Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors. EMBO J 23(9):1922-33 SGD PMID 15103325
  2. Reggiori F, et al. (2004) The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 6(1):79-90 SGD PMID 14723849
  3. Barth H, et al. (2001) Autophagy and the cytoplasm to vacuole targeting pathway both require Aut10p. FEBS Lett 508(1):23-8 SGD PMID 11707261

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