YFL025C

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Systematic name YFL025C
Gene name BST1
Aliases
Feature type ORF, Verified
Coordinates Chr VI:87232..84143
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Description of YFL025C: GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules[1][2]



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References

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  1. Tanaka S, et al. (2004) Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p. J Biol Chem 279(14):14256-63 SGD PMID 14734546
  2. Elrod-Erickson MJ and Kaiser CA (1996) Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations. Mol Biol Cell 7(7):1043-58 SGD PMID 8862519

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