Difference between revisions of "YFL009W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001885 YFL009W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CDC4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CDC4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VI:116139..118478 | |nowrap| Chr VI:116139..118478 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001885 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YFL009W:''' F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p<ref name='S000058226'>Skowyra D, et al. (1997) F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91(2):209-19 {{SGDpaper|S000058226}} PMID 9346238</ref><ref name='S000045265'>Goh PY and Surana U (1999) Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae. Mol Cell Biol 19(8):5512-22 {{SGDpaper|S000045265}} PMID 10409741</ref><ref name='S000041398'>Feldman RM, et al. (1997) A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91(2):221-30 |
{{SGDpaper|S000041398}} PMID 9346239</ref> | {{SGDpaper|S000041398}} PMID 9346239</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
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| Systematic name | YFL009W |
| Gene name | CDC4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:116139..118478 |
| Primary SGDID | S000001885 |
Description of YFL009W: F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p[1][2][3]
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References
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- ↑ Skowyra D, et al. (1997) F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91(2):209-19 SGD PMID 9346238
- ↑ Goh PY and Surana U (1999) Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae. Mol Cell Biol 19(8):5512-22 SGD PMID 10409741
- ↑ Feldman RM, et al. (1997) A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91(2):221-30 SGD PMID 9346239
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