YER179W
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| Systematic name | YER179W |
| Gene name | DMC1 |
| Aliases | ISC2 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:548421..549517 |
| Primary SGDID | S000000981 |
Description of YER179W: Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein; binds ssDNA and dsDNA, forms helical filaments; stimulated by Rdh54p[1][2][3][4]
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References
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- ↑ Bishop DK, et al. (1992) DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69(3):439-56 SGD PMID 1581960
- ↑ Nimonkar AV, et al. (2012) Saccharomyces cerevisiae Dmc1 and Rad51 preferentially function with Tid1 and Rad54, respectively, to promote DNA strand invasion during genetic recombination. J Biol Chem () SGD PMID 22761450
- ↑ Schwacha A and Kleckner N (1997) Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90(6):1123-35 SGD PMID 9323140
- ↑ Symington LS (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 66(4):630-70, table of contents SGD PMID 12456786
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