Difference between revisions of "YER154W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000956 YER154W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000956 YER154W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''OXA1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''OXA1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:475015..476223
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|nowrap| Chr V:475020..476228
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000956
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000956
 
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'''Description of YER154W:''' Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals<ref name='S000075522'>Szyrach G, et al. (2003) Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondria. EMBO J 22(24):6448-57 {{SGDpaper|S000075522}} PMID 14657018</ref><ref name='S000075521'>Jia L, et al. (2003) Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. EMBO J 22(24):6438-47 {{SGDpaper|S000075521}} PMID 14657017</ref><ref name='S000050616'>Bonnefoy N, et al. (1994) Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 91(25):11978-82
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'''Description of YER154W:''' Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals<ref name='S000050616'>Bonnefoy N, et al. (1994) Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 91(25):11978-82 {{SGDpaper|S000050616}} PMID 7991568</ref><ref name='S000075521'>Jia L, et al. (2003) Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. EMBO J 22(24):6438-47 {{SGDpaper|S000075521}} PMID 14657017</ref><ref name='S000075522'>Szyrach G, et al. (2003) Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondria. EMBO J 22(24):6448-57
  {{SGDpaper|S000050616}} PMID 7991568</ref>
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  {{SGDpaper|S000075522}} PMID 14657018</ref>
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YER154W
Gene name OXA1
Aliases PET1402
Feature type ORF, Verified
Coordinates Chr V:475020..476228
Primary SGDID S000000956


Description of YER154W: Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals[1][2][3]




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References

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  1. Bonnefoy N, et al. (1994) Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 91(25):11978-82 SGD PMID 7991568
  2. Jia L, et al. (2003) Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. EMBO J 22(24):6438-47 SGD PMID 14657017
  3. Szyrach G, et al. (2003) Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondria. EMBO J 22(24):6448-57 SGD PMID 14657018

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