Difference between revisions of "YER139C"

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'''Description of YER139C:''' Protein with a role in transcription; interacts with Rpo21p; has a cysteine-rich motif required for function and conserved in eukaryotes; shuttles between the nucleus and cytoplasm; RTR1 shows genetic interactions with RPB4, 5, 7, and 9<ref name='S000057998'>Smith V, et al. (1996) Functional analysis of the genes of yeast chromosome V by genetic footprinting. Science 274(5295):2069-74 {{SGDpaper|S000057998}} PMID 8953036</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000126089'>Gibney PA, et al. (2008) Rtr1 is the Saccharomyces cerevisiae homolog of a novel family of RNA polymerase II-binding proteins. Eukaryot Cell 7(6):938-48
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'''Description of YER139C:''' CTD phosphatase; dephosphorylates S5-P in the C-terminal domain of Rpo21p; has a cysteine-rich motif required for function and conserved in eukaryotes; shuttles between the nucleus and cytoplasm<ref name='S000126089'>Gibney PA, et al. (2008) Rtr1 is the Saccharomyces cerevisiae homolog of a novel family of RNA polymerase II-binding proteins. Eukaryot Cell 7(6):938-48 {{SGDpaper|S000126089}} PMID 18408053</ref><ref name='S000131322'>Mosley AL, et al. (2009) Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation. Mol Cell 34(2):168-78
  {{SGDpaper|S000126089}} PMID 18408053</ref>
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  {{SGDpaper|S000131322}} PMID 19394294</ref>
 
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Revision as of 14:05, 23 September 2009

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Systematic name YER139C
Gene name RTR1
Aliases
Feature type ORF, Verified
Coordinates Chr V:451238..450558
Primary SGDID S000000941


Description of YER139C: CTD phosphatase; dephosphorylates S5-P in the C-terminal domain of Rpo21p; has a cysteine-rich motif required for function and conserved in eukaryotes; shuttles between the nucleus and cytoplasm[1][2]




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References

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  1. Gibney PA, et al. (2008) Rtr1 is the Saccharomyces cerevisiae homolog of a novel family of RNA polymerase II-binding proteins. Eukaryot Cell 7(6):938-48 SGD PMID 18408053
  2. Mosley AL, et al. (2009) Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation. Mol Cell 34(2):168-78 SGD PMID 19394294

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