Difference between revisions of "YER126C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YER126C YER126C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000928 YER126C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NSA2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NSA2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:414175..413390
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|nowrap| Chr V:414179..413394
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000928
 
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'''Description of {{PAGENAME}}:''' Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis<ref name='S000076470'>Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 {{SGDpaper|S000076470}} PMID 15100437</ref><ref name='S000066002'>Harnpicharnchai P, et al. (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15
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'''Description of YER126C:''' Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA<ref name='S000066002'>Harnpicharnchai P, et al. (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15 {{SGDpaper|S000066002}} PMID 11583614</ref><ref name='S000076470'>Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 {{SGDpaper|S000076470}} PMID 15100437</ref><ref name='S000117369'>Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108
  {{SGDpaper|S000066002}} PMID 11583614</ref>
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  {{SGDpaper|S000117369}} PMID 16861225</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Genetic ====
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[[Category:Topic:Interactions:Genetic]]
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YER126C is a suppressor of  NOG1 [[Category:Genetic Interaction with NOG1]]
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'''Mutation type(s)''': overexpression, Thermosensitive
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<ref name='S000117369'>Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108 {{SGDpaper|S000117369}} PMID 16861225</ref> <ref name = 'CAset9088-2006-08-01'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9088 Alice Lebreton] on 2006-08-01</ref>
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==== Two Hybrid ====
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[[Category:Topic:Interactions:Two Hybrid]]
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Two Hybrid interaction with NOG1 [[Category:Two Hybrid Interactions with NOG1]]<br> <ref name='S000117369'>Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108 {{SGDpaper|S000117369}} PMID 16861225</ref> <ref name = 'CAset9088-2006-08-01'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9088 Alice Lebreton] on 2006-08-01</ref>
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=== Protein Details ===
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[[Category:Topic:Protein Details]]
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==== Protein Degradation ====
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[[Category:Topic:Protein Details:Protein Degradation]]
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Nsa2 is unstable when large ribosomal subunit biogenesis is blocked upstream of this factor. <ref name='S000117369'>Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108 {{SGDpaper|S000117369}} PMID 16861225</ref> <ref name = 'CAset9088-2006-08-01'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9088 Alice Lebreton] on 2006-08-01</ref>
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{{ShortCenteredHR}}
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==== Protein Function/Process ====
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[[Category:Topic:Protein Details:Protein Function/Process]]
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required for the processing of ITS2 in 27SB pre-rRNAs. <ref name='S000117369'>Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108 {{SGDpaper|S000117369}} PMID 16861225</ref> <ref name = 'CAset9088-2006-08-01'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9088 Alice Lebreton] on 2006-08-01</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YER126C
Gene name NSA2
Aliases
Feature type ORF, Verified
Coordinates Chr V:414179..413394
Primary SGDID S000000928


Description of YER126C: Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA[1][2][3]




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Community Commentary

About Community Commentary. Please share your knowledge!

Interactions

Genetic

YER126C is a suppressor of NOG1

Mutation type(s): overexpression, Thermosensitive

[3] [4]

Two Hybrid

Two Hybrid interaction with NOG1
[3] [4]


Protein Details

Protein Degradation

Nsa2 is unstable when large ribosomal subunit biogenesis is blocked upstream of this factor. [3] [4]


Protein Function/Process

required for the processing of ITS2 in 27SB pre-rRNAs. [3] [4]





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References

See Help:References on how to add references

  1. Harnpicharnchai P, et al. (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15 SGD PMID 11583614
  2. Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 SGD PMID 15100437
  3. 3.0 3.1 3.2 3.3 3.4 Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108 SGD PMID 16861225 Cite error: Invalid <ref> tag; name "S000117369" defined multiple times with different content Cite error: Invalid <ref> tag; name "S000117369" defined multiple times with different content Cite error: Invalid <ref> tag; name "S000117369" defined multiple times with different content Cite error: Invalid <ref> tag; name "S000117369" defined multiple times with different content
  4. 4.0 4.1 4.2 4.3 submitted by Alice Lebreton on 2006-08-01

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