YER116C

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Systematic name YER116C
Gene name SLX8
Aliases
Feature type ORF, Verified
Coordinates Chr V:396168..395344
Primary SGDID S000000918


Description of YER116C: Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate[1][2][3]




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References

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  1. Xie Y, et al. (2007) The yeast HEX3-SLX8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J Biol Chem SGD PMID 17848550
  2. Wang Z, et al. (2006) Genetic Analysis Connects SLX5 and SLX8 to the SUMO Pathway in Saccharomyces cerevisiae. Genetics 172(3):1499-509 SGD PMID 16387868
  3. Mullen JR, et al. (2001) Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157(1):103-18 SGD PMID 11139495

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