Difference between revisions of "YER088C"

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'''Description of YER088C:''' Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; similar to Tod6p; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation<ref name='S000043169'>Lorenz MC and Heitman J (1998) Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. Genetics 150(4):1443-57 {{SGDpaper|S000043169}} PMID 9832522</ref><ref name='S000128493'>Shevchenko A, et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9(11):R167 {{SGDpaper|S000128493}} PMID 19040720</ref><ref name='S000047238'>Singer MS, et al. (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32 {{SGDpaper|S000047238}} PMID 9755194</ref><ref name='S000129025'>Zhu C, et al. (2009) High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res 19(4):556-66
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'''Description of YER088C:''' Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation; DOT6 has a paralog, TOD6, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000043169'>Lorenz MC and Heitman J (1998) Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. Genetics 150(4):1443-57 {{SGDpaper|S000043169}} PMID 9832522</ref><ref name='S000128493'>Shevchenko A, et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9(11):R167 {{SGDpaper|S000128493}} PMID 19040720</ref><ref name='S000047238'>Singer MS, et al. (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32 {{SGDpaper|S000047238}} PMID 9755194</ref><ref name='S000129025'>Zhu C, et al. (2009) High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res 19(4):556-66
 
  {{SGDpaper|S000129025}} PMID 19158363</ref>
 
  {{SGDpaper|S000129025}} PMID 19158363</ref>
 
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Latest revision as of 14:05, 12 September 2012

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Systematic name YER088C
Gene name DOT6
Aliases PBF2
Feature type ORF, Verified
Coordinates Chr V:335188..333176
Primary SGDID S000000890


Description of YER088C: Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation; DOT6 has a paralog, TOD6, that arose from the whole genome duplication[1][2][3][4][5]




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References

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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Lorenz MC and Heitman J (1998) Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. Genetics 150(4):1443-57 SGD PMID 9832522
  3. Shevchenko A, et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9(11):R167 SGD PMID 19040720
  4. Singer MS, et al. (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32 SGD PMID 9755194
  5. Zhu C, et al. (2009) High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res 19(4):556-66 SGD PMID 19158363

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