Difference between revisions of "YEL062W"

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'''Description of YEL062W:''' Component, with Npr3p, of an evolutionarily conserved complex that mediates downregulation of TOR Complex 1 activity in response to amino acid limitation; transcription is induced in response to proline and urea<ref name='S000046769'>Rousselet G, et al. (1995) A second nitrogen permease regulator in Saccharomyces cerevisiae. FEBS Lett 359(2-3):215-9 {{SGDpaper|S000046769}} PMID 7867803</ref><ref name='S000073889'>Schenk PW, et al. (2003) Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill. Mol Pharmacol 64(2):259-68 {{SGDpaper|S000073889}} PMID 12869630</ref><ref name='S000130605'>Neklesa TK and Davis RW (2009) A Genome-Wide Screen for Regulators of TORC1 in Response to Amino Acid Starvation Reveals a Conserved Npr2/3 Complex. PLoS Genet 5(6):e1000515
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'''Description of YEL062W:''' Component, with Npr3p, of an evolutionarily conserved complex that mediates downregulation of TOR Complex 1 activity in response to amino acid limitation; transcription is induced in response to proline and urea<ref name='S000130605'>Neklesa TK and Davis RW (2009) A Genome-Wide Screen for Regulators of TORC1 in Response to Amino Acid Starvation Reveals a Conserved Npr2/3 Complex. PLoS Genet 5(6):e1000515 {{SGDpaper|S000130605}} PMID 19521502</ref><ref name='S000046769'>Rousselet G, et al. (1995) A second nitrogen permease regulator in Saccharomyces cerevisiae. FEBS Lett 359(2-3):215-9 {{SGDpaper|S000046769}} PMID 7867803</ref><ref name='S000073889'>Schenk PW, et al. (2003) Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill. Mol Pharmacol 64(2):259-68
{{SGDpaper|S000130605}} PMID 19521502</ref>
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{{SGDpaper|S000073889}} PMID 12869630</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YEL062W
Gene name NPR2
Aliases
Feature type ORF, Verified
Coordinates Chr V:34407..36254
Primary SGDID S000000788


Description of YEL062W: Component, with Npr3p, of an evolutionarily conserved complex that mediates downregulation of TOR Complex 1 activity in response to amino acid limitation; transcription is induced in response to proline and urea[1][2][3]




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References

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  1. Neklesa TK and Davis RW (2009) A Genome-Wide Screen for Regulators of TORC1 in Response to Amino Acid Starvation Reveals a Conserved Npr2/3 Complex. PLoS Genet 5(6):e1000515 SGD PMID 19521502
  2. Rousselet G, et al. (1995) A second nitrogen permease regulator in Saccharomyces cerevisiae. FEBS Lett 359(2-3):215-9 SGD PMID 7867803
  3. Schenk PW, et al. (2003) Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill. Mol Pharmacol 64(2):259-68 SGD PMID 12869630

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