YEL034W

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Systematic name YEL034W
Gene name HYP2
Aliases TIF51A
Feature type ORF, Verified
Coordinates Chr V:85676..86149


Description of YEL034W: Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification[1][2][3]




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References

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  1. Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66 SGD PMID 16914118
  2. Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 SGD PMID 11861547
  3. Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 SGD PMID 8314769

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