Difference between revisions of "YEL031W"
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==Community Commentary== | ==Community Commentary== | ||
Revision as of 11:51, 24 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YEL031W | |
| Gene name | SPF1 | |
| Aliases | COD1, PER9, PIO1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr V:90258..93905 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YEL031W: P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1[1][2][3]
Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Genotype: RHY1202
Phenotype(s): Loss of function (Null), Recessive, Viable
Deletion of COD1/SPF1 prevents the degradation of Hmg2p from being regulated. [2] [4]
References
See Help:References on how to add references
- ↑ Cronin SR, et al. (2002) Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis. J Cell Biol 157(6):1017-28 SGD PMID 12058017
- ↑ 2.0 2.1 Cronin SR, et al. (2000) Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol 148(5):915-24 SGD PMID 10704442
- ↑ Suzuki C and Shimma YI (1999) P-type ATPase spf1 mutants show a novel resistance mechanism for the killer toxin SMKT. Mol Microbiol 32(4):813-23 SGD PMID 10361284
- ↑ submitted by Stephen R. Cronin on 2003-06-13
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