Difference between revisions of "YDR520C"

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'''Description of YDR520C:''' Putative transcription factor containing a (Zn(II)2Cys6 motif; GFP-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and sensitive to caffeine; similar to S. kluyveri Urc2p involved in uracil catabolism<ref name='S000126674'>Andersen G, et al. (2008) A second pathway to degrade pyrimidine nucleic acid precursors in eukaryotes. J Mol Biol 380(4):656-66 {{SGDpaper|S000126674}} PMID 18550080</ref><ref name='S000114011'>Guo X, et al. (2006) Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae. Bioinformatics 22(4):392-9 {{SGDpaper|S000114011}} PMID 16339282</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000069948'>Akache B, et al. (2001) Phenotypic analysis of genes encoding yeast zinc cluster proteins. Nucleic Acids Res 29(10):2181-90
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'''Description of YDR520C:''' Putative Zn(II)2Cys6 motif containing transcription factor; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; similar to S. kluyveri Urc2p involved in uracil catabolism<ref name='S000129563'>Hontz RD, et al. (2009) Genetic Identification of Factors that Modulate Ribosomal DNA Transcription in Saccharomyces cerevisiae. Genetics {{SGDpaper|S000129563}} PMID 19270272</ref><ref name='S000126674'>Andersen G, et al. (2008) A second pathway to degrade pyrimidine nucleic acid precursors in eukaryotes. J Mol Biol 380(4):656-66 {{SGDpaper|S000126674}} PMID 18550080</ref><ref name='S000114011'>Guo X, et al. (2006) Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae. Bioinformatics 22(4):392-9 {{SGDpaper|S000114011}} PMID 16339282</ref><ref name='S000069948'>Akache B, et al. (2001) Phenotypic analysis of genes encoding yeast zinc cluster proteins. Nucleic Acids Res 29(10):2181-90
 
  {{SGDpaper|S000069948}} PMID 11353088</ref>
 
  {{SGDpaper|S000069948}} PMID 11353088</ref>
 
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Revision as of 14:05, 20 March 2009

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Systematic name YDR520C
Gene name URC2
Aliases RRT4
Feature type ORF, Uncharacterized
Coordinates Chr IV:1483396..1481078
Primary SGDID S000002928


Description of YDR520C: Putative Zn(II)2Cys6 motif containing transcription factor; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; similar to S. kluyveri Urc2p involved in uracil catabolism[1][2][3][4]




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References

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  1. Hontz RD, et al. (2009) Genetic Identification of Factors that Modulate Ribosomal DNA Transcription in Saccharomyces cerevisiae. Genetics SGD PMID 19270272
  2. Andersen G, et al. (2008) A second pathway to degrade pyrimidine nucleic acid precursors in eukaryotes. J Mol Biol 380(4):656-66 SGD PMID 18550080
  3. Guo X, et al. (2006) Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae. Bioinformatics 22(4):392-9 SGD PMID 16339282
  4. Akache B, et al. (2001) Phenotypic analysis of genes encoding yeast zinc cluster proteins. Nucleic Acids Res 29(10):2181-90 SGD PMID 11353088

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