YDR508C

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Systematic name YDR508C
Gene name GNP1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1468436..1466445
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Description of YDR508C: High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids[1][2][3][4]



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References

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  1. Eckert-Boulet N, et al. (2005) Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae. Curr Genet 47(3):139-49 SGD PMID 15611869
  2. Forsberg H, et al. (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28 SGD PMID 11679080
  3. Zhu X, et al. (1996) GNP1, the high-affinity glutamine permease of S. cerevisiae. Curr Genet 30(2):107-14 SGD PMID 8660458
  4. Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 SGD PMID 10654085

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