Difference between revisions of "YDR508C"

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'''Description of YDR508C:''' High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids<ref name='S000080129'>Eckert-Boulet N, et al. (2005) Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae. Curr Genet 47(3):139-49 {{SGDpaper|S000080129}} PMID 15611869</ref><ref name='S000066134'>Forsberg H, et al. (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28 {{SGDpaper|S000066134}} PMID 11679080</ref><ref name='S000047477'>Zhu X, et al. (1996) GNP1, the high-affinity glutamine permease of S. cerevisiae. Curr Genet 30(2):107-14 {{SGDpaper|S000047477}} PMID 8660458</ref><ref name='S000043244'>Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28
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'''Description of YDR508C:''' High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids<ref name='S000043244'>Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 {{SGDpaper|S000043244}} PMID 10654085</ref><ref name='S000047477'>Zhu X, et al. (1996) GNP1, the high-affinity glutamine permease of S. cerevisiae. Curr Genet 30(2):107-14 {{SGDpaper|S000047477}} PMID 8660458</ref><ref name='S000080129'>Eckert-Boulet N, et al. (2005) Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae. Curr Genet 47(3):139-49 {{SGDpaper|S000080129}} PMID 15611869</ref><ref name='S000066134'>Forsberg H, et al. (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28
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  {{SGDpaper|S000066134}} PMID 11679080</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YDR508C
Gene name GNP1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1468437..1466446
Primary SGDID S000002916


Description of YDR508C: High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [5] [6]


Other Topic: expression

Specifically lower expression in nitrogen limited chemostat cultures versus nitrogen excess. [5] [6]





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References

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  1. Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 SGD PMID 10654085
  2. Zhu X, et al. (1996) GNP1, the high-affinity glutamine permease of S. cerevisiae. Curr Genet 30(2):107-14 SGD PMID 8660458
  3. Eckert-Boulet N, et al. (2005) Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae. Curr Genet 47(3):139-49 SGD PMID 15611869
  4. Forsberg H, et al. (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28 SGD PMID 11679080
  5. 5.0 5.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. 6.0 6.1 submitted by Viktor Boer on 2003-07-25

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