Difference between revisions of "YDR495C"

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'''Description of YDR495C:''' Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase<ref name='S000039392'>Rothman JH, et al. (1989) Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. J Cell Biol 109(1):93-100 {{SGDpaper|S000039392}} PMID 2526133</ref><ref name='S000045321'>Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 {{SGDpaper|S000045321}} PMID 3062374</ref><ref name='S000047885'>Raymond CK, et al. (1990) Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J Cell Biol 111(3):877-92 {{SGDpaper|S000047885}} PMID 2202738</ref><ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50
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'''Description of YDR495C:''' Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase<ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 {{SGDpaper|S000122612}} PMID 17488625</ref><ref name='S000047885'>Raymond CK, et al. (1990) Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J Cell Biol 111(3):877-92 {{SGDpaper|S000047885}} PMID 2202738</ref><ref name='S000045321'>Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 {{SGDpaper|S000045321}} PMID 3062374</ref><ref name='S000039392'>Rothman JH, et al. (1989) Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. J Cell Biol 109(1):93-100
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Revision as of 13:05, 25 February 2010

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Systematic name YDR495C
Gene name VPS3
Aliases PEP6, VPL3, VPT17
Feature type ORF, Verified
Coordinates Chr IV:1441143..1438108
Primary SGDID S000002903


Description of YDR495C: Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase[1][2][3][4]




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References

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  1. Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 SGD PMID 17488625
  2. Raymond CK, et al. (1990) Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J Cell Biol 111(3):877-92 SGD PMID 2202738
  3. Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 SGD PMID 3062374
  4. Rothman JH, et al. (1989) Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. J Cell Biol 109(1):93-100 SGD PMID 2526133

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