YDR493W

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Systematic name YDR493W
Gene name MZM1
Aliases AIM8, FMP36
Feature type ORF, Verified
Coordinates Chr IV:1436217..1436588
Primary SGDID S000002901


Description of YDR493W: Protein required for assembly of the cytochrome bc(1) complex; facilitates insertion of Rip1p into the complex at a late stage of assembly; localized to the mitochondrial matrix; null mutant exhibits a respiratory growth defect and reduced mitochondrial zinc levels, which is characteristic of mutations affecting bc(1) complex assembly; conserved in metazoans[1][2]




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References

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  1. Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem 285(25):19450-9 SGD PMID 20404342
  2. Atkinson A, et al. (2011) The LYR protein Mzm1 functions in the insertion of the Rieske Fe/S protein in yeast mitochondria. Mol Cell Biol () SGD PMID 21807901

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