Difference between revisions of "YDR481C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002889 YDR481C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002889 YDR481C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO8 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO8 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''phoH''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1420242..1418542
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|nowrap| Chr IV:1420250..1418550
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002889
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002889
 
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'''Description of YDR481C:''' Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides<ref name='S000046576'>Klionsky DJ and Emr SD (1989) Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J 8(8):2241-50 {{SGDpaper|S000046576}} PMID 2676517</ref><ref name='S000045672'>Kaneko Y, et al. (1985) Transcriptional and post-transcriptional control of PHO8 expression by PHO regulatory genes in Saccharomyces cerevisiae. Mol Cell Biol 5(1):248-52 {{SGDpaper|S000045672}} PMID 2984552</ref><ref name='S000044193'>Donella-Deana A, et al. (1993) Specific dephosphorylation of phosphopeptides by the yeast alkaline phosphatase encoded by PHO8 gene. Biochim Biophys Acta 1177(2):221-8
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'''Description of YDR481C:''' Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN<ref name='S000044193'>Donella-Deana A, et al. (1993) Specific dephosphorylation of phosphopeptides by the yeast alkaline phosphatase encoded by PHO8 gene. Biochim Biophys Acta 1177(2):221-8 {{SGDpaper|S000044193}} PMID 8499492</ref><ref name='S000045672'>Kaneko Y, et al. (1985) Transcriptional and post-transcriptional control of PHO8 expression by PHO regulatory genes in Saccharomyces cerevisiae. Mol Cell Biol 5(1):248-52 {{SGDpaper|S000045672}} PMID 2984552</ref><ref name='S000046576'>Klionsky DJ and Emr SD (1989) Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J 8(8):2241-50
  {{SGDpaper|S000044193}} PMID 8499492</ref>
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  {{SGDpaper|S000046576}} PMID 2676517</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YDR481C
Gene name PHO8
Aliases phoH
Feature type ORF, Verified
Coordinates Chr IV:1420250..1418550
Primary SGDID S000002889


Description of YDR481C: Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN[1][2][3]




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References

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  1. Donella-Deana A, et al. (1993) Specific dephosphorylation of phosphopeptides by the yeast alkaline phosphatase encoded by PHO8 gene. Biochim Biophys Acta 1177(2):221-8 SGD PMID 8499492
  2. Kaneko Y, et al. (1985) Transcriptional and post-transcriptional control of PHO8 expression by PHO regulatory genes in Saccharomyces cerevisiae. Mol Cell Biol 5(1):248-52 SGD PMID 2984552
  3. Klionsky DJ and Emr SD (1989) Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J 8(8):2241-50 SGD PMID 2676517

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