Difference between revisions of "YDR480W"

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'''Description of YDR480W:''' Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription<ref name='S000052329'>Bardwell L, et al. (1998) Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc Natl Acad Sci U S A 95(26):15400-5 {{SGDpaper|S000052329}} PMID 9860980</ref><ref name='S000045641'>Cook JG, et al. (1996) Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev 10(22):2831-48 {{SGDpaper|S000045641}} PMID 8918885</ref><ref name='S000071763'>Gelli A (2002) Rst1 and Rst2 are required for the a/alpha diploid cell type in yeast. Mol Microbiol 46(3):845-54 {{SGDpaper|S000071763}} PMID 12410840</ref><ref name='S000046547'>Olson KA, et al. (2000) Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms. Mol Cell Biol 20(12):4199-209
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'''Description of YDR480W:''' MAP kinase-responsive inhibitor of the Ste12p transcription factor, involved in the regulation of mating-specific genes and the invasive growth pathway; related regulators Dig1p and Dig2p bind to Ste12p<ref name='S000052329'>Bardwell L, et al. (1998) Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc Natl Acad Sci U S A 95(26):15400-5 {{SGDpaper|S000052329}} PMID 9860980</ref><ref name='S000045641'>Cook JG, et al. (1996) Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev 10(22):2831-48 {{SGDpaper|S000045641}} PMID 8918885</ref><ref name='S000071763'>Gelli A (2002) Rst1 and Rst2 are required for the a/alpha diploid cell type in yeast. Mol Microbiol 46(3):845-54 {{SGDpaper|S000071763}} PMID 12410840</ref><ref name='S000136721'>McCullagh E, et al. (2010) Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway. Nat Cell Biol 12(10):954-962 {{SGDpaper|S000136721}} PMID 20852627</ref><ref name='S000046547'>Olson KA, et al. (2000) Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms. Mol Cell Biol 20(12):4199-209
 
  {{SGDpaper|S000046547}} PMID 10825185</ref>
 
  {{SGDpaper|S000046547}} PMID 10825185</ref>
 
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Revision as of 14:05, 4 November 2010

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Systematic name YDR480W
Gene name DIG2
Aliases RST2
Feature type ORF, Verified
Coordinates Chr IV:1417392..1418363
Primary SGDID S000002888


Description of YDR480W: MAP kinase-responsive inhibitor of the Ste12p transcription factor, involved in the regulation of mating-specific genes and the invasive growth pathway; related regulators Dig1p and Dig2p bind to Ste12p[1][2][3][4][5]




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References

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  1. Bardwell L, et al. (1998) Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc Natl Acad Sci U S A 95(26):15400-5 SGD PMID 9860980
  2. Cook JG, et al. (1996) Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev 10(22):2831-48 SGD PMID 8918885
  3. Gelli A (2002) Rst1 and Rst2 are required for the a/alpha diploid cell type in yeast. Mol Microbiol 46(3):845-54 SGD PMID 12410840
  4. McCullagh E, et al. (2010) Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway. Nat Cell Biol 12(10):954-962 SGD PMID 20852627
  5. Olson KA, et al. (2000) Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms. Mol Cell Biol 20(12):4199-209 SGD PMID 10825185

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