Difference between revisions of "YDR469W"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:17, 30 January 2007

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Systematic name YDR469W
Gene name SDC1
Aliases CPS25, SAF19
Feature type ORF, Verified
Coordinates Chr IV:1399007..1399534


Description of YDR469W: Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30[1][2][3][4][5]




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Community Commentary

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References

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  1. Dover J, et al. (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277(32):28368-71 SGD PMID 12070136
  2. Sun ZW and Allis CD (2002) Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418(6893):104-8 SGD PMID 12077605
  3. Krogan NJ, et al. (2002) COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. J Biol Chem 277(13):10753-5 SGD PMID 11805083
  4. Roguev A, et al. (2001) The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J 20(24):7137-48 SGD PMID 11742990
  5. Miller T, et al. (2001) COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proc Natl Acad Sci U S A 98(23):12902-7 SGD PMID 11687631

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