Difference between revisions of "YDR469W"
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| − | '''Description of YDR469W:''' Subunit of the COMPASS (Set1C) complex, which methylates lysine 4 of histone H3 and is required in chromatin silencing at telomeres; contains a Dpy-30 domain that mediates interaction with Bre2p; similar to C. elegans and human DPY-30<ref name='S000066156'>Miller T, et al. (2001) COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proc Natl Acad Sci U S A 98(23):12902-7 {{SGDpaper|S000066156}} PMID 11687631</ref><ref name='S000068755'>Roguev A, et al. (2001) The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J 20(24):7137-48 {{SGDpaper|S000068755}} PMID 11742990</ref><ref name='S000070308'>Dover J, et al. (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277(32):28368-71 {{SGDpaper|S000070308}} PMID 12070136</ref><ref name='S000070076'>Sun ZW and Allis CD (2002) Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418(6893):104-8 {{SGDpaper|S000070076}} PMID 12077605</ref><ref name='S000069538'>Krogan NJ, et al. (2002) COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. J Biol Chem 277(13):10753-5 {{SGDpaper|S000069538}} PMID 11805083</ref><ref name='S000132201'>South PF, et al. ( | + | '''Description of YDR469W:''' Subunit of the COMPASS (Set1C) complex, which methylates lysine 4 of histone H3 and is required in chromatin silencing at telomeres; contains a Dpy-30 domain that mediates interaction with Bre2p; similar to C. elegans and human DPY-30<ref name='S000066156'>Miller T, et al. (2001) COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proc Natl Acad Sci U S A 98(23):12902-7 {{SGDpaper|S000066156}} PMID 11687631</ref><ref name='S000068755'>Roguev A, et al. (2001) The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J 20(24):7137-48 {{SGDpaper|S000068755}} PMID 11742990</ref><ref name='S000070308'>Dover J, et al. (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277(32):28368-71 {{SGDpaper|S000070308}} PMID 12070136</ref><ref name='S000070076'>Sun ZW and Allis CD (2002) Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418(6893):104-8 {{SGDpaper|S000070076}} PMID 12077605</ref><ref name='S000069538'>Krogan NJ, et al. (2002) COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. J Biol Chem 277(13):10753-5 {{SGDpaper|S000069538}} PMID 11805083</ref><ref name='S000132201'>South PF, et al. (2010) A conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression. J Biol Chem 285(1):595-607 |
{{SGDpaper|S000132201}} PMID 19897479</ref> | {{SGDpaper|S000132201}} PMID 19897479</ref> | ||
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Revision as of 14:05, 2 January 2010
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| Systematic name | YDR469W |
| Gene name | SDC1 |
| Aliases | CPS25, SAF19 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1399008..1399535 |
| Primary SGDID | S000002877 |
Description of YDR469W: Subunit of the COMPASS (Set1C) complex, which methylates lysine 4 of histone H3 and is required in chromatin silencing at telomeres; contains a Dpy-30 domain that mediates interaction with Bre2p; similar to C. elegans and human DPY-30[1][2][3][4][5][6]
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References
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- ↑ Miller T, et al. (2001) COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proc Natl Acad Sci U S A 98(23):12902-7 SGD PMID 11687631
- ↑ Roguev A, et al. (2001) The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J 20(24):7137-48 SGD PMID 11742990
- ↑ Dover J, et al. (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277(32):28368-71 SGD PMID 12070136
- ↑ Sun ZW and Allis CD (2002) Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418(6893):104-8 SGD PMID 12077605
- ↑ Krogan NJ, et al. (2002) COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. J Biol Chem 277(13):10753-5 SGD PMID 11805083
- ↑ South PF, et al. (2010) A conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression. J Biol Chem 285(1):595-607 SGD PMID 19897479
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