Difference between revisions of "YDR456W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002864 YDR456W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002864 YDR456W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NHX1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NHX1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1367477..1369378
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|nowrap| Chr IV:1367485..1369386
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002864
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002864
 
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'''Description of YDR456W:''' Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; required for osmotolerance to acute hypertonic shock<ref name='S000080349'>Brett CL, et al. (2005) The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking. Mol Biol Cell 16(3):1396-405 {{SGDpaper|S000080349}} PMID 15635088</ref><ref name='S000051567'>Nass R, et al. (1997) Intracellular sequestration of sodium by a novel Na+/H+ exchanger in yeast is enhanced by mutations in the plasma membrane H+-ATPase. Insights into mechanisms of sodium tolerance. J Biol Chem 272(42):26145-52 {{SGDpaper|S000051567}} PMID 9334180</ref><ref name='S000042739'>Nass R and Rao R (1999) The yeast endosomal Na+/H+ exchanger, Nhx1, confers osmotolerance following acute hypertonic shock. Microbiology 145 ( Pt 11):3221-8
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'''Description of YDR456W:''' Na+/H+ and K+/H+ exchanger, required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion<ref name='S000080349'>Brett CL, et al. (2005) The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking. Mol Biol Cell 16(3):1396-405 {{SGDpaper|S000080349}} PMID 15635088</ref><ref name='S000042739'>Nass R and Rao R (1999) The yeast endosomal Na+/H+ exchanger, Nhx1, confers osmotolerance following acute hypertonic shock. Microbiology 145 ( Pt 11):3221-8 {{SGDpaper|S000042739}} PMID 10589731</ref><ref name='S000051567'>Nass R, et al. (1997) Intracellular sequestration of sodium by a novel Na+/H+ exchanger in yeast is enhanced by mutations in the plasma membrane H+-ATPase. Insights into mechanisms of sodium tolerance. J Biol Chem 272(42):26145-52 {{SGDpaper|S000051567}} PMID 9334180</ref><ref name='S000136282'>Qiu QS and Fratti RA (2010) The Na+/H+ exchanger Nhx1p regulates the initiation of Saccharomyces cerevisiae vacuole fusion. J Cell Sci 123(Pt 19):3266-75
  {{SGDpaper|S000042739}} PMID 10589731</ref>
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  {{SGDpaper|S000136282}} PMID 20826459</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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==References==
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==References==
 
==References==

Latest revision as of 07:45, 23 January 2012

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Systematic name YDR456W
Gene name NHX1
Aliases NHA2, VPL27, VPS44
Feature type ORF, Verified
Coordinates Chr IV:1367485..1369386
Primary SGDID S000002864


Description of YDR456W: Na+/H+ and K+/H+ exchanger, required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion[1][2][3][4]




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Community Commentary

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References

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  1. Brett CL, et al. (2005) The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking. Mol Biol Cell 16(3):1396-405 SGD PMID 15635088
  2. Nass R and Rao R (1999) The yeast endosomal Na+/H+ exchanger, Nhx1, confers osmotolerance following acute hypertonic shock. Microbiology 145 ( Pt 11):3221-8 SGD PMID 10589731
  3. Nass R, et al. (1997) Intracellular sequestration of sodium by a novel Na+/H+ exchanger in yeast is enhanced by mutations in the plasma membrane H+-ATPase. Insights into mechanisms of sodium tolerance. J Biol Chem 272(42):26145-52 SGD PMID 9334180
  4. Qiu QS and Fratti RA (2010) The Na+/H+ exchanger Nhx1p regulates the initiation of Saccharomyces cerevisiae vacuole fusion. J Cell Sci 123(Pt 19):3266-75 SGD PMID 20826459

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References

See Help:References on how to add references

See Help:Categories on how to add the wiki page for this gene to a Category </protect>