YDR453C
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| Systematic name | YDR453C | |
| Gene name | TSA2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr IV:1365654..1365064 | |
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Description of YDR453C: Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants [1][2][3][4]
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References
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- ↑ Munhoz DC and Netto LE (2004) Cytosolic thioredoxin peroxidase I and II are important defenses of yeast against organic hydroperoxide insult: catalases and peroxiredoxins cooperate in the decomposition of H2O2 by yeast. J Biol Chem 279(34):35219-27 SGD PMID 15210711
- ↑ Wong CM, et al. (2004) Peroxiredoxin-null yeast cells are hypersensitive to oxidative stress and are genomically unstable. J Biol Chem 279(22):23207-13 SGD PMID 15051715
- ↑ Wong CM, et al. (2002) Cooperation of yeast peroxiredoxins Tsa1p and Tsa2p in the cellular defense against oxidative and nitrosative stress. J Biol Chem 277(7):5385-94 SGD PMID 11741925
- ↑ Park SG, et al. (2000) Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae. J Biol Chem 275(8):5723-32 SGD PMID 10681558
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