Difference between revisions of "YDR420W"

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'''Description of YDR420W:''' Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection<ref name='S000055885'>Yabe T, et al. (1996) HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae. J Bacteriol 178(2):477-83 {{SGDpaper|S000055885}} PMID 8550469</ref><ref name='S000130285'>Pitoniak A, et al. (2009) The Signaling Mucins Msb2 and Hkr1 Differentially Regulate the Filamentation MAPK Pathway and Contribute to a Multimodal Response. Mol Biol Cell {{SGDpaper|S000130285}} PMID 19439450</ref><ref name='S000123317'>Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33
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'''Description of YDR420W:''' Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection<ref name='S000055885'>Yabe T, et al. (1996) HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae. J Bacteriol 178(2):477-83 {{SGDpaper|S000055885}} PMID 8550469</ref><ref name='S000130285'>Pitoniak A, et al. (2009) The signaling mucins Msb2 and Hkr1 differentially regulate the filamentation mitogen-activated protein kinase pathway and contribute to a multimodal response. Mol Biol Cell 20(13):3101-14 {{SGDpaper|S000130285}} PMID 19439450</ref><ref name='S000123317'>Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33
 
  {{SGDpaper|S000123317}} PMID 17627274</ref>
 
  {{SGDpaper|S000123317}} PMID 17627274</ref>
 
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Revision as of 14:05, 4 July 2009

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Systematic name YDR420W
Gene name HKR1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1306260..1311668
Primary SGDID S000002828


Description of YDR420W: Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection[1][2][3]




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References

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  1. Yabe T, et al. (1996) HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae. J Bacteriol 178(2):477-83 SGD PMID 8550469
  2. Pitoniak A, et al. (2009) The signaling mucins Msb2 and Hkr1 differentially regulate the filamentation mitogen-activated protein kinase pathway and contribute to a multimodal response. Mol Biol Cell 20(13):3101-14 SGD PMID 19439450
  3. Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33 SGD PMID 17627274

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