Difference between revisions of "YDR420W"
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| − | '''Description of YDR420W:''' | + | '''Description of YDR420W:''' Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection<ref name='S000055885'>Yabe T, et al. (1996) HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae. J Bacteriol 178(2):477-83 {{SGDpaper|S000055885}} PMID 8550469</ref><ref name='S000130285'>Pitoniak A, et al. (2009) The Signaling Mucins Msb2 and Hkr1 Differentially Regulate the Filamentation MAPK Pathway and Contribute to a Multimodal Response. Mol Biol Cell {{SGDpaper|S000130285}} PMID 19439450</ref><ref name='S000123317'>Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33 |
{{SGDpaper|S000123317}} PMID 17627274</ref> | {{SGDpaper|S000123317}} PMID 17627274</ref> | ||
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Revision as of 14:05, 5 June 2009
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| Systematic name | YDR420W |
| Gene name | HKR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1306260..1311668 |
| Primary SGDID | S000002828 |
Description of YDR420W: Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection[1][2][3]
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References
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- ↑ Yabe T, et al. (1996) HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae. J Bacteriol 178(2):477-83 SGD PMID 8550469
- ↑ Pitoniak A, et al. (2009) The Signaling Mucins Msb2 and Hkr1 Differentially Regulate the Filamentation MAPK Pathway and Contribute to a Multimodal Response. Mol Biol Cell SGD PMID 19439450
- ↑ Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33 SGD PMID 17627274
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