Difference between revisions of "YDR419W"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
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| Systematic name | YDR419W |
| Gene name | RAD30 |
| Aliases | DBH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1303166..1305064 |
Description of YDR419W: DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins[1][2][3][4]
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References
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- ↑ Washington MT, et al. (2003) The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol Cell Biol 23(22):8316-22 SGD PMID 14585988
- ↑ Prakash S and Prakash L (2002) Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev 16(15):1872-83 SGD PMID 12154119
- ↑ Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 SGD PMID 10713149
- ↑ Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4 SGD PMID 9974380
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